Human Clone's Birth Predicted


Infertility researcher Panos Zavos predicted yesterday that his Kentucky-based human cloning team will produce a pregnancy this year, with the delivery of a cloned human being coming in 2003.

 

Only logistical problems, not scientific or medical ones, now stand in the way of the team's attempts to clone a person, he said after testifying before a congressional subcommittee debating whether any form of cloning should be made illegal in this country.

 

Zavos said his nine-person team, which includes physicians, physiologists and laboratory technicians, has established two overseas sites where the cloning procedure will occur. He wouldn't name the countries, although he said one is in Europe and the other is in the region "between Greece and India."

 

He said that the laboratory and clinical facilities are ready but that problems still exist in matters ranging from securing visas for patients to ensuring they will have comfortable accommodations and good food.

 

"It's a matter of logistics now," he told reporters in a hallway outside the hearing room where he had answered questions from members of the House Government Reform subcommittee on criminal justice, drug policy and human resources.

 

In the hearing, he said unequivocally more than once that his team has not yet cloned and implanted a human embryo. He also said he wouldn't clone a human being in the United States in any case, given the popular opposition to the idea.

 

He did tell the panel, however, that the cloning "genie is out of the bottle and it keeps getting bigger every day. There is no way that this genie is going back into the bottle."

 

Formerly on the faculty of the University of Kentucky and now an infertility treatment entrepreneur, Zavos said his team is one of five in the world planning to clone human beings. He said he knows of efforts underway in Russia and China, although he wouldn't say whether he has had contact with the people involved in those efforts.

 

The other teams include one headed by Severino Antinori, who directs a human reproduction research center in Rome and until recently was a collaborator of Zavos, and one affiliated with the Raelians, a small religious sect with members in Canada and Britain.

 

Recent rumors and at least one newspaper report published last month said three women are now carrying cloned fetuses created by Antinori. Zavos, however, said he does not believe the reports, noting only that "I happen to have some inside information." He promised that when his group achieves its first pregnancy, "we will show you the evidence."

 

He said his group has screened and approved 12 couples who want to have a child through cloning. In five of the couples, one or both partners are physicians.

 

The couples come from several countries, and each has exhausted other methods of reproducing, Zavos said. The criteria for approval are the same as those he and his colleagues use for candidates seeking in-vitro fertilization (IVF).

 

Recent success rates in the cloning of mice and cattle have led the Kentucky team to believe that the likelihood of success in human beings will approximate that of IVF, he said. That technique requires, on average, the implantation of 12 to 14 embryos over numerous menstrual cycles to get one gestation that is carried to term, Zavos added.

 

The team includes people who are able to treat problem pregnancies or malformed infants, and to terminate a pregnancy if necessary. The decision whether to abort a fetus will be made by the couple involved, he said.

 

He disputed the assertion, made by subcommittee chairman Mark Edward Souder (R-Ind.), that "all clones so far have been found to suffer from severe abnormalities, premature aging and early death."

 

"This is such an untrue statement," Zavos said. "I don't know why he doesn't put himself under oath."

 

Zavos, 58, is a native of Cyprus who immigrated to the United States in 1966. He has a doctorate in physiology, not a medical degree. He did not offer objective evidence supporting his assertions about the readiness of his team, but he said a British documentary producer is accompanying him on his trips overseas and recording the preparations on film.

 

Yesterday's House subcommittee hearing was unusual in that the House has already passed a bill that would ban both cloning for the purposes of reproduction and cloning to produce cells that could be used to treat disease (therapeutic cloning). The Senate is considering two types of cloning bills: ones that would ban all cloning, and ones that would ban reproductive cloning only. Senate aides said it appeared the hearing was called to try to increase support for a ban on all forms of cloning.

 

May 16, 2002


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